Submit to IU IRB

An Institutional Review Board (IRB), sometimes called an Ethics Review Committee, is responsible for reviewing and approving, or disapproving, research with human subjects. IRBs may be associated with a research university, such as the IU IRBs, or they may be independent (sometimes called commercial or central IRBs), such as WCG, Advarra, or the NCI’s Central IRB (CIRB). All human subjects research conducted at IU or at one of its clinical partners, including IU Health and Eskenazi Health, must receive Institutional Review Board (IRB) approval before the research can begin. 

Sponsor or funding requirements may propose which IRB (IU IRBs or external IRBs such as WCG or Advarra) should review a particular study, however, the IU IRB must still agree to this plan. This means that even if you plan to use another IRB, you must first submit an application to the IU IRB to start this process (referred to as a Request to Rely). The IU IRB must approve the Request to Rely before the study may be submitted to another IRB for review.